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I have been on Capecitabine since 2010 and haven't had any side effects with this medication. I was diagnosed with breast cancer in 2009 and since that time have tried many medications and undergone two chemotherapies. I believe it's due to Capecitabine that I haven't lost my hair and had no complications after the chemotherapies. In general I have wonderful results without side effects. I am now 41, the cancer seems to have stepped aside and I am looking forward to many more years of continued good health.
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Capecitabine is usually taken for 14 days followed by a 7-day rest period (no drug), for a 21-day cycle.
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Continue your regular dosing schedule and check with your doctor.
It is very unlikely that you nicked your pudendal nerve but if your discomfort does not resolve in a few days, perhaps you can consult with your medical provider for an evaluation.
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In a drug interaction study with single-dose warfarin administration, there was a significant increase in the mean AUC of S-warfarin.
Postmarketing reports indicate that some patients receiving XELODA and phenytoin had toxicity associated with elevated phenytoin levels.
The adverse reaction profile of capecitabine was consistent with the known adverse reaction profile in adults, with the exception of laboratory abnormalities which occurred more commonly in pediatric patients.
After being on the drug for a few weeks and having tests come back, I discovered that the cancer was no longer spreading through my system.
If SO it would be less likely to require Xeloda, because in such cases it is said to do no good.
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It is received through IV and repeated every 2 weeks.
Do not use medications containing fluorouracil while using capecitabine.
Report any signs of bleeding or bruising (such as black stools) to your doctor immediately.
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Because capecitabine is principally activated within tumours, it has relatively few effects on normal tissues, and therefore relatively few side-effects.
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The primary endpoint was progression-free-survival (PFS) from randomisation following the induction phase; secondary endpoints included overall survival (OS) from randomisation following the induction phase, overall response rate (ORR) and safety.
Very rarely, capecitabine my exacerbate coronary artery disease, causing angina, or occasionally myocardial infarction or irregular heart rhythms.
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Perhaps it is based on the number of lymph nodes effected by the cancer?
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In addition, evaluation for autoimmune disease or Lyme disease may be indicated in some patients.
These effects get better in some people after the drug is stopped but it does not get better in all people.
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Her doctor assured her, had she taken the natural herbal juice, it would have sped her cancer up even more as the herbs in that juice would have prevented her chemo from doing its job.
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The enzyme, thymidine phosphorylase (dThdPase), then hydrolyzes 5'-DFUR to the active drug 5-FU.
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Click on citations within drug and disease topics in our clinical reference to review the clinical evidence on MEDLINE.
We encourage participation from both you and your family to make certain you are comfortable with all decisions made regarding your treatment.
It would take them 9 hours to infuse the oxal because my body was so sensitive that I would have horrible pain in my arms, muscle cramps in my throat, hands, and feet.
HER2-targeted therapy using either antibody-based therapy or a small molecule tyrosine kinase inhibitor (TKI) has led to significant and ongoing improvements in disease free survival (DFS), progression free survival (PFS) and overall survival (OS) in both the adjuvant and metastatic settings.
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You should take the tablet within 30 minutes of eating a meal.
If a grade 4 experience occurs, therapy should be discontinued or interrupted until resolved or decreased to grade 1, and therapy should be restarted at 50% of the original dose.
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Could be from the inflammation xeloda is causing, could be xeloda is not working for me and the cancer is spreading.
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Other studies, however, are continuing to evaluate the role of Erbitux in the treatment of pancreatic cancer.
However, there are certain patient subgroups for whom first-line combination therapy may not be the most appropriate treatment strategy.
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However, the pudendal nerve motor terminal latency test was used in the past.
We present results of the early secondary endpoints.
Perhaps the most important preventive measure is for patients to be meticulously educated about the frequency and early recognition of treatment-associated rashes, to prevent severe manifestations of the dermatologic syndrome.
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There may be other brand names for this medicine.
It belongs to a class of drugs called antimetabolites.
Other than warfarin, no formal drug-drug interaction studies between XELODA and other CYP2C9 substrates have been conducted.
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XELODA has a low potential for pharmacokinetic interactions related to plasma protein binding.
Researchers from Taiwan have reported that patients with Stage IVA pancreatic cancer who were treated with radiation therapy plus Gemzar chemotherapy fared better than those treated with radiation therapy plus 5-FU chemotherapy.
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Do not take more or less of it or take it more often than prescribed by your doctor.
This program provides financial assistance to eligible individuals to cover coinsurance, copayments, healthcare premiums and deductibles for certain treatments.
Over this range, the pharmacokinetics of XELODA and its metabolite, 5'-DFCR were dose proportional and did not change over time.
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What other drugs will affect capecitabine?
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Hi, My dad has been told that he has 10 lesions on the right side of his brain and they did a MRI to find the primary source which is in his lung.
If no cancer cells are there, doctors call it a “pathologic complete response.
The mean duration of treatment was 129 days in the combination arm and 98 days in the monotherapy arm.
The polyps that were removed didn't seem to cause him too much concern.
Mine, however, falls into the other camp: it did work for a period of time.
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Capecitabine is also in the early stages of evaluation in combination with oral irinotecan, thus offering potential for all-oral combination therapy for patients with colorectal cancer.
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This leaflet answers some common questions about XELODA tablets.
Stop taking XELODA and call your doctor right away if you have any of these symptoms and you are not able to do your usual activities.
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