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I have been on Capecitabine since 2010 and haven't had any side effects with this medication. I was diagnosed with breast cancer in 2009 and since that time have tried many medications and undergone two chemotherapies. I believe it's due to Capecitabine that I haven't lost my hair and had no complications after the chemotherapies. In general I have wonderful results without side effects. I am now 41, the cancer seems to have stepped aside and I am looking forward to many more years of continued good health.

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Continue your regular dosing schedule and check with your doctor.

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Postmarketing reports indicate that some patients receiving XELODA and phenytoin had toxicity associated with elevated phenytoin levels.

The adverse reaction profile of capecitabine was consistent with the known adverse reaction profile in adults, with the exception of laboratory abnormalities which occurred more commonly in pediatric patients.

After being on the drug for a few weeks and having tests come back, I discovered that the cancer was no longer spreading through my system.

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Do not use medications containing fluorouracil while using capecitabine.

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The primary endpoint was progression-free-survival (PFS) from randomisation following the induction phase; secondary endpoints included overall survival (OS) from randomisation following the induction phase, overall response rate (ORR) and safety.

Very rarely, capecitabine my exacerbate coronary artery disease, causing angina, or occasionally myocardial infarction or irregular heart rhythms.

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In addition, evaluation for autoimmune disease or Lyme disease may be indicated in some patients.

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HER2-targeted therapy using either antibody-based therapy or a small molecule tyrosine kinase inhibitor (TKI) has led to significant and ongoing improvements in disease free survival (DFS), progression free survival (PFS) and overall survival (OS) in both the adjuvant and metastatic settings.

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You should take the tablet within 30 minutes of eating a meal.

If a grade 4 experience occurs, therapy should be discontinued or interrupted until resolved or decreased to grade 1, and therapy should be restarted at 50% of the original dose.

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It belongs to a class of drugs called antimetabolites.

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XELODA has a low potential for pharmacokinetic interactions related to plasma protein binding.

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Over this range, the pharmacokinetics of XELODA and its metabolite, 5'-DFCR were dose proportional and did not change over time.

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If no cancer cells are there, doctors call it a “pathologic complete response.

The mean duration of treatment was 129 days in the combination arm and 98 days in the monotherapy arm.

The polyps that were removed didn't seem to cause him too much concern.

Mine, however, falls into the other camp: it did work for a period of time.

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Capecitabine is also in the early stages of evaluation in combination with oral irinotecan, thus offering potential for all-oral combination therapy for patients with colorectal cancer.

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This leaflet answers some common questions about XELODA tablets.

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