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I am taking Gleevec after surgery, to remove 15ccmm tumor. It has been 7 months and I am tumor free. The main side effects of taking Gleevec has been abdominal bloating with pain, at times severe. I am able to handle the side effects for the most part, but when it becomes too much, I just reduce my dose for a few days until I feel better, normally or for two days a week. I was on Gleevec for 5 months prior to surgery. It didn't reduce the tumor, but it stop its growth and reduced the density considerably.
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Eleven of 28 patients had received radiation therapy, and 4 had received chemotherapy (BCNU) prior to temozolomide.
However, using E-64-d, a calpain and cathepsin inhibitor, or CA074-Me, a cathepsin B inhibitor, we were unable to prevent p21 decrease in response to imatinib.
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Lowe (New York, NY, USA) reported that similar tumours react completely differently to specific treatments.
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Outcome was analyzed on the basis of pre- and post-treatment Karnofsky performance scale (KPS) and on survival.
Tumor removal surgeries have been documented in ancient Egypt, hormone therapy was developed in 1896, and radiation therapy was developed in 1899.
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Mean time to local progression had been 14 months, mean age at diagnosis, 5 years.
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An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
What do kinase inhibition profiles tell us about tyrosine kinase inhibitors used for the treatment of CML?
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