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I am taking Gleevec after surgery, to remove 15ccmm tumor. It has been 7 months and I am tumor free. The main side effects of taking Gleevec has been abdominal bloating with pain, at times severe. I am able to handle the side effects for the most part, but when it becomes too much, I just reduce my dose for a few days until I feel better, normally or for two days a week. I was on Gleevec for 5 months prior to surgery. It didn't reduce the tumor, but it stop its growth and reduced the density considerably.

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Eleven of 28 patients had received radiation therapy, and 4 had received chemotherapy (BCNU) prior to temozolomide.

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What do kinase inhibition profiles tell us about tyrosine kinase inhibitors used for the treatment of CML?

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